Fecundity and Twinning Rates as Measures of Fertility Before Diagnosis of Germ-Cell Testicular Cancer
نویسندگان
چکیده
منابع مشابه
genetics of testicular germ cell tumors
testicular germ cell tumor (tgct) is the most solid tumor in 20-40 years old man. tgct account for 95% of testicular tumors and represent a unique type of human cancer from several different perspectives. tgct arise by transformation of germ cells. the transformed germ cells exhibit ploripotentially to differentiate into embryonic. extra-embryonic, and somatic tissue types, and are highly sensi...
متن کاملIncreased risk of testicular germ cell cancer among infertile men.
BACKGROUND The risk of testicular cancer is thought to be higher among men seeking infertility treatment compared with the general population. Confirmation of this risk in a large US cohort of at-risk patients is lacking. This study explored the association between male infertility and subsequent development of testicular cancer in a US-based cohort. METHODS A total of 51 461 couples evaluate...
متن کاملBilateral testicular germ cell tumors.
Testicular cancer represents 1% to 1.5% of neoplasias in males and 5% of urologic tumors in general. The incidence of bilateral testicular tumors is 1-5%. Approximately one third of the cases are diagnosed as synchronous, while the other two thirds are diagnosed as metachronous tumors. Additionally, 5% of all patients diagnosed with testicular cancer may have contralateral intratubular germ cel...
متن کاملExpression Analysis of RNA-Binding Motif Gene on Y Chromosome (RBMY) Protein Isoforms in Testis Tissue and a Testicular Germ Cell Cancer-Derived Cell Line (NT2)
a key factor in spermatogenesis and disorders associated with this protein have been recognized to be related to male infertility. Although it was suggested that this protein could have different functions during germ cell development, no studies have been conducted to uncover the mechanism of this potential function yet. Here, we analyzed the expression pattern of RBMY protein isoforms in test...
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ژورنال
عنوان ژورنال: JNCI Journal of the National Cancer Institute
سال: 2004
ISSN: 0027-8874,1460-2105
DOI: 10.1093/jnci/djh012